gspread loses connection with the Google API probably every 10 minutes. This can be easily tackled by calling a function or Class which reconnects to the database.
import gspread
from oauth2client.service_account import ServiceAccountCredentials
from datetime import datetime
from datetime import timedelta
def connect_database():
scope = ['https://spreadsheets.google.com/feeds', 'https://www.googleapis.com/auth/drive']
creds = ServiceAccountCredentials.from_json_keyfile_name('client_secret.json', scope)
client = gspread.authorize(creds)
workbook1 = client.open("File_Name")
w1 = workbook1.worksheet("Sheet1")
w2 = workbook1.worksheet("Sheet2")
return w1,w2
program_start_time=datetime.now()
if datetime.now() > program_start_time + timedelta(minutes=10):
worksheet1, worksheet2 = connect_database()
program_start_time = datetime.now() #Resets the Program Start Time